- Molecules that bind to an enzyme and decrease the effect of the active enzyme
- Can be reversible or irreversible
- Competitive
- Bind at the active site
- Competes with the substrate
- Can be overcome by a high concentration of substrate
- Inhibitor typically has a similar structure to the substrate
- Non-competitive
- Bind to the enzyme and decrease the effect, but do not affect binding of the substrate
- Depends on the concentration of the inhibitor
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